Late June.
Gusu University.
Sangge Asia Pacific Resource Center.
Inside a certain laboratory.
Chen Yu, wearing a white lab coat, looked at the plastic bag in front of him with a hint of a smile.
Inside the plastic bag were some powdered substances.
It was — Universal Artificial Blood!
Since early May, when Chen Yu launched the artificial blood project, he had been using his spare time to try to synthesize universal blood artificially.
Hard work pays off!
Under Chen Yu's exceptional medical skills.
The universal artificial blood that the medical community had been unable to develop for half a century was easily developed in his hands.
This artificial blood is a completely synthetic hemoglobin, falling under the category of biological innovative drugs.
It can replace the hemoglobin in human blood that carries oxygen and contains a large amount of red blood cells and blood type antibodies.
The artificial blood is stored in a plastic bag.
It can be stored dry at room temperature for a year.
The synthetic red blood cells contained within.
They are only two percent the size of human red blood cells.
When needed, inject sterile water to mix and use.
During the development of artificial blood.
Chen Yu used a cell membrane component called liposomes to create extremely tiny "bags" and then filled them with hemostatic and oxygen transport components.
At the same time, he used gene knockout techniques to knock out the antigens on the surface of blood cells, making blood transfusions no longer require matching, achieving a truly universal artificial blood!
Inside the laboratory.
The 10 medical undergraduates in the research group all looked at Chen Yu with fervent eyes.
If it was earlier.
They were all amazed by Chen Yu's profound medical knowledge.
Then, during their time in the research group.
The 10 medical undergraduates were completely convinced by Chen Yu's formidable research capabilities!
Everyone knew.
As "project participants" of universal artificial blood, they had a chance to go down in history with Professor Chen Yu in the future!
At this moment, Chen Yu looked around at everyone and said, "Now, everyone report on the progress of your research projects, starting with Qin Shuang."
"Yes, Professor!"
Qin Shuang stepped forward and reported in detail, "After the artificial blood was successfully developed, we immediately carried out animal testing.
The first test subjects were mice.
We replaced the entire blood of the mice three times, carrying out a 300% blood exchange, leaving only 5% of their own blood.
The new blood composition of these mice is 5% of their own blood and 95% universal artificial blood.
Under these circumstances.
The vital signs of the mice were very stable.
Without artificial intervention.
They could survive healthily.
Next.
The mice's new blood constantly emerged.
In just one week.
Their original 95% of artificial blood was basically eliminated.
Two weeks later.
The mice's new blood completely replaced the artificial blood.
They were lively and full of energy, jumping around.
In terms of specific data.
Of the 72 mice, none died after using the universal artificial blood!"
As the words fell.
Everyone had smiles on their faces.
During this animal testing research, they had been constantly taking blood from the mice.
Tail blood collection, orbital blood collection, jugular vein blood collection, saphenous vein blood collection, facial blood collection, cardiac blood collection, and abdominal aorta blood collection, etc., all kinds of methods.
During the experiment.
They were prepared to lose a batch of mice.
Unexpectedly...
The universal artificial blood was extremely effective, able to completely replace the mice's own blood.
A student named Ning Feng from the research group stepped forward and said, "Professor Chen, in addition to carrying out animal experiments on mice, we have also conducted blood exchange experiments on 64 rats, 56 rabbits, 85 beagles, 56 rhesus monkeys, 65 crab-eating macaques, 70 woolly monkeys, 65 miniature pigs, etc.
In terms of experimental data.
Universal artificial blood has a miraculous effect on these animals.
After blood collection, animals that were weak, after receiving artificial blood, their antibodies would take effect to prevent any incompatibility between the artificial blood and animal blood.
Based on this, we have drawn a preliminary conclusion.
Universal artificial blood can supplement the blood required by many types of anemic animals."
"Very good!"
Chen Yu nodded in satisfaction.
He slowly said, "After the research group was established, I formulated a four-step development plan for the development of universal artificial blood.
Right now, the first three steps have been successfully completed.
Only the last step remains — human trials on volunteers!
This step, while seemingly simple, is actually the most important.
If human trials fail.
Then all our previous efforts will be in vain."
Hearing this.
The students all looked serious.
Universal artificial blood actually falls under the category of drug development.
The road to drug development is long!
Generally speaking.
From laboratory confirmation of target discovery to a series of preclinical studies, it takes two to three years.
Preclinical related experiments also take two to three years.
Carrying out Phase I clinical trials, Phase II clinical trials, and Phase III clinical trials takes three to seven years.
After all clinical trials are completed.
It also has to go through the long process of new drug approval.
Once all stages are complete, a new drug can be officially approved for market.
Of course...
The head of their research group is medical giant Chen Yu.
Professor Chen, from the artificial synthesis of hemoglobin to the development of universal artificial blood, only took one week.
The preclinical trial stage, the research group spent over a month on the evaluation of the pharmacological and toxicological effects of universal artificial blood, quality research, stability research, animal experiments, and other aspects.
With the completion of animal experiments.
The research group can carry out Phase I clinical trials, that is, human trials on specific groups.
To be honest.
Such rapid research progress.
The medical world has never seen it before!
The more they interacted with Professor Chen.
The more they realized that Professor Chen was incredibly talented, his drug development skills were unbelievable!
Research teams in the outside world, often couldn't achieve research progress in ten years, but Professor Chen could often complete it in just a few days.
As members of the research group.
This was the first time they felt that research was so simple!
Although human clinical trials have not yet begun.
But they were all confident.
The universal artificial blood developed by Professor Chen will definitely benefit countless anemic patients and usher in a revolutionary change in the medical field!